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Newrotex develops innovative silk-based medical
solutions for the nervous system.
Newrotex develops innovative silk-based medical
solutions for the nervous system.
The answer to “Can you repair nerves?” shouldn’t come with caveats. This is why Newrotex is set to disrupt existing approaches to surgical nerve repair. We’re on track to provide an alternative to autografts, the current gold standard in treatment for nerve injuries. A gold standard that requires sacrificing a healthy nerve from another part of the body. With our patented silk-based technology, we’ll deliver an off-the-shelf solution for surgical repair of the nerve. Without the need for long, complicated operations or using expensive donor tissues, Newrotex makes immediate treatment possible for patients who have suffered nerve injuries due to trauma, medical conditions, or surgical treatments.
Annual operations for nerve injuries
Newrotex silk-based nerve products address the shortcomings of the solutions currently available.
Most of the world’s 1.5 million annual operations for nerve injuries are treated with autografts requiring a second injury and long surgery times, along with risking donor site morbidity and infection.
All of the major current solutions – autografts, allografts, and hollow tube conduits – are limited when repairing large gaps in nerves. Read Current Approaches for more about these and other shortcomings with current solutions for peripheral nerve repair.
Over the past few decades, the potential biomedical applications of silk have been gaining interest at an exponential rate.
The versatility created by silk’s chemical structure allows for the production of fibres, gels, scaffolds, films, membranes, and powders. Silk has shown to have excellent cell affinity, and being biocompatible, with the ability to tailor biodegradation, silk is an ideal candidate for biomedical applications.
In terms of nerve repair, luminal silk fibres inside a vein or conduit guide regenerating axons, while the bioabsorbable, permeable tube allows nutrients to support nerve regeneration. Furthermore, silk products can be stored at room temperature, thereby removing the need for expensive cold storage and transportation.
Our first product is a 10cm implant made from bundles of luminal spider silk fibres that can be implanted into a vein or inserted into hollow conduits to support nerve re-growth. Pre-clinical studies have show that SilkAxons® support superior axonal regeneration.
Our second product is an off-the-shelf silk-based peripheral nerve conduit pre-filled with enhancing luminal silk fibres, negating the need to use a vein.
The fibres have proven nerve-regenerating properties and clinical trials show them to be comparable or superior to autografts. And with a porous tubular biocompatible sheath designed to encourage vascularisation, we provide a new and better approach to treating patients with peripheral nerve injuries.
Newrotex launched a first-in-human clinical trial in Q3 2025 using SilkAxons® to bridge large nerve gaps of up to 10cm (significantly more than current FDA approved devices). This study will generate foundational data for Newrotex’s global clinical strategy. Our goal is to commence a large study this year culminating in an application for market approval in the USA and UK. We are also developing collaborations in which our silk platform technology may lead to further improvements in patient care, such as Schwann cell delivery and spinal cord injury repair.
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Dorcel had attempted a bridge-building strategy: placing trailers on Vimeo, running a podcast on Spotify about “cinema of desire,” and partnering with a respectable French film magazine for a roundtable. By mid-2023, all of those partnerships quietly ended. A Vimeo staffer leaked that Dorcel’s Silk & Silicon trailer was flagged not for nudity but for “suggestive context” in its thumbnail. The algorithmic message was clear: there is no safe space for erotic art in mainstream social media.
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The most prosaic explanation is the one that also toppled Netflix’s animated slate and Max’s live-action library: the post-2022 streaming bubble burst. Dorcel had aggressively expanded its direct-to-consumer platform, Dorcel Vision, during the pandemic, betting on a subscriber model similar to Netflix. By 2023, however, user acquisition costs had skyrocketed, and venture capital for adult-adjacent tech had dried up following stricter banking regulations (more on that below).
By September 2023, users on the r/oculusnsfw and r/DataHoarder subreddits began noticing discrepancies. Metadata for upcoming Dorcel releases vanished from IMDb-like adult databases. The official Dorcel Vision streaming platform, which typically announced quarterly slates, fell silent. A planned September release titled The Curator (a horror-erotic hybrid directed by a known Spanish cult filmmaker) missed its date. By December, references to 2023 as a “production year” were wiped from the company’s corporate website, replaced by a generic “New Classics” collection of remastered 1990s titles.
To keep up with elusive releases, digital creators are often the best source of news. Organizations like the World Federation of Advertisers have even launched dedicated Creator Forums to bridge the gap between studios and the audience.
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